Collagen is the most abundant protein in the human body, forming the structural foundation for skin, hair, nails, bones, joints, and connective tissues. As we age, natural collagen production declines, contributing to wrinkles, joint discomfort, and reduced skin elasticity. Collagen supplementation has surged in popularity worldwide, including in the UAE, due to its potential benefits for skin, hair, and overall structural health.

This article serves as a comprehensive cluster reference, covering collagen types, benefits, dosage, side effects, and safety considerations.

What Is Collagen?

Collagen is a fibrous protein composed of amino acids like glycine, proline, and hydroxyproline. It is critical for:

• Skin elasticity and hydration

• Bone density and joint integrity

• Tendon, ligament, and cartilage strength

• Hair and nail growth

Declining collagen with age starts around the late 20s and accelerates in the 40s, which is why supplementation is popular.

Types of Collagen

Different types of collagen serve distinct roles in the body:

 

Multi-collagen peptides often combine Types I, II, III, and sometimes Types V & X, for comprehensive support.

Evidence-Based Benefits of Collagen

1. Skin, Hair & Nails

• Type I and III are particularly important for skin elasticity and hydration.

• Clinical studies show improvements in wrinkle depth, skin smoothness, and hydration with 2.5–10 g/day of hydrolyzed collagen over 8–12 weeks.

• Collagen may also strengthen hair and nails, reducing brittleness.

2. Joint & Bone Health

• Type II supports cartilage health, reducing joint pain and improving mobility.

• Studies in osteoarthritis patients show improvements in joint comfort and function with collagen hydrolysates.

3. Muscle Mass & Recovery

• Collagen is rich in amino acids necessary for muscle repair, especially when combined with resistance training.

4. Collagen Benefits for Women and Men

Forms of Collagen Supplements

Recommended Dosage

 

Best time to take collagen:

• Morning or evening, with or without meals

• Combining with vitamin C can enhance collagen synthesis

Collagen Side Effects & Safety

• Generally well-tolerated

• Possible minor digestive issues: bloating, heartburn, diarrhea

• Allergic reactions possible if derived from marine or bovine sources

• No significant long-term safety concerns reported with standard doses

Always check for quality certifications, especially for marine or multi-collagen products.

Collagen-Rich Foods

Collagen can also be supported via dietary intake:

 

Dietary intake complements supplementation for optimal results.

Common Myths & Misconceptions

References

1. Zague, V. (2008). A new view concerning the effects of collagen hydrolysate intake on skin properties. Arch Dermatol Res, 300(9), 479–483. https://doi.org/10.1007/s00403-008-0890-2

2. Bello, A. E., & Oesser, S. (2006). Collagen hydrolysate for the treatment of osteoarthritis and other joint disorders: A review of the literature. Current Medical Research and Opinion, 22(11), 2221–2232. https://doi.org/10.1185/030079906X148373

3. Clark, K. L., Sebastianelli, W., Flechsenhar, K. R., et al. (2008). 24-week study on collagen hydrolysate for improving joint pain in athletes. Current Medical Research and Opinion, 24(5), 1485–1496. https://doi.org/10.1185/030079908X291967

4. NIH Office of Dietary Supplements. (2023). Collagen: Fact Sheet for Health Professionals. https://ods.od.nih.gov/factsheets/Collagen-HealthProfessional/

5. Schunck, M., et al. (2015). Oral collagen peptides supplementation improves skin elasticity, hydration and dermal collagen density. Journal of Medicinal Food, 18(10), 1235–1241. https://doi.org/10.1089/jmf.2015.0040

6. Ohara, H., et al. (2010). Effect of oral collagen peptide on skin hydration and biochemical properties. Journal of Nutritional Science and Vitaminology, 56(6), 367–372.