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Ashwagandha: Benefits, Dosage, Side Effects & Safety

by Subhash Rao 14 Jan 2026

Ashwagandha (Withania somnifera), also known as Indian ginseng or winter cherry, is one of the most widely used herbs in Ayurvedic medicine. In recent years, it has gained mainstream popularity across wellness, sports nutrition, stress management, and hormonal health — particularly in regions like the UAE, where interest in adaptogens is rising.

This article serves as a comprehensive, evergreen reference hub on ashwagandha, addressing what it does, who benefits most, how to dose it safely, and where confusion or misuse commonly occurs.

What Is Ashwagandha and Why Is It Considered an Adaptogen?

Ashwagandha is classified as an adaptogen, meaning it helps the body adapt to physical, mental, and emotional stressors. Rather than stimulating or sedating the nervous system directly, adaptogens work by supporting balance — particularly through the hypothalamic-pituitary-adrenal (HPA) axis, which regulates cortisol and stress response.

The primary bioactive compounds in ashwagandha are withanolides, which are believed to contribute to its effects on stress, inflammation, cognition, and hormonal signaling.

Evidence-Based Benefits of Ashwagandha

1. Stress Reduction & Cortisol Regulation

One of the most well-established benefits of ashwagandha is its role in lowering perceived stress and cortisol levels. Research consistently shows improvements in stress scores, sleep quality, and emotional resilience when ashwagandha is used for 6–8 weeks.

This makes it particularly relevant for:

  • Chronic stress and burnout

  • High-pressure work environments

  • Sleep disturbances linked to stress

2. Ashwagandha Benefits for Men

Ashwagandha has been widely studied in men, especially in relation to:

  • Testosterone levels

  • Sperm quality and motility

  • Muscle strength and recovery

These benefits appear to be more pronounced in men experiencing high stress, suboptimal testosterone levels, or fertility challenges.

Benefit Area

Observed Effect

Testosterone

Modest increases, especially in deficient men

Fertility

Improved sperm count & motility

Exercise performance

Enhanced strength & recovery


3. Ashwagandha Benefits for Women

For women, ashwagandha’s impact is more indirect but highly relevant, particularly through stress and hormonal regulation.

Common benefits include:

  • Reduced anxiety and emotional fatigue

  • Support during PMS and stress-related cycle irregularities

  • Improved sleep quality

  • Support during perimenopause when cortisol and sleep disruption increase

Women’s Health Area

Potential Support

Stress & anxiety

Reduced stress perception

Sleep

Faster sleep onset, deeper sleep

Hormonal balance

Indirect support via cortisol regulation

Important note: Ashwagandha does not act like estrogen or progesterone, which is a common misconception. Its hormonal effects are mediated through stress pathways.

4. Cognitive Function & Brain Health

Ashwagandha has been shown to support:

  • Memory

  • Focus and attention

  • Mental clarity

These effects are thought to be linked to its anti-inflammatory and antioxidant activity, as well as reduced stress-related cognitive impairment.

5. Blood Sugar, Inflammation & General Metabolic Health

Emerging evidence suggests potential benefits in:

  • Improving insulin sensitivity

  • Reducing markers of low-grade inflammation

  • Supporting overall metabolic resilience

These effects are supportive rather than therapeutic and should not replace medical management.

Forms of Ashwagandha: Powder vs Tablets vs Extracts

Ashwagandha is available in multiple forms, which often causes confusion for consumers.

Form

Description

Best For

Powder

Traditional root powder

Ayurveda purists, custom dosing

Tablets/Capsules

Standardized extracts

Convenience & consistency

Liquid extracts

Faster absorption

Those with digestion issues

Standardized extracts (e.g., KSM-66®, Sensoril®) specify withanolide content, which improves dosing accuracy and research alignment.

Ashwagandha Dosage: What Is Considered Safe and Effective?

Most clinical studies use 300–600 mg per day of a standardized root extract.

Goal

Typical Dosage

Stress & anxiety

300–600 mg/day

Sleep support

300 mg in the evening

Athletic performance

500–600 mg/day

Key dosing tips:

  • Start low and assess tolerance

  • Take with food to reduce GI discomfort

  • Consistency matters more than timing

Ashwagandha Side Effects & Safety Considerations

Ashwagandha is generally well tolerated, but side effects can occur.

Possible Side Effects

  • Digestive discomfort

  • Drowsiness (especially at higher doses)

  • Headache in sensitive individuals

Who Should Be Cautious?

Group

Reason for Caution

Pregnancy

Insufficient safety data

Thyroid conditions

May increase thyroid hormone levels

Autoimmune disorders

Immune-modulating effects

Sedative medications

Additive calming effect

 

A common misuse is combining ashwagandha with multiple calming supplements, leading to excessive fatigue.

Ashwagandha in the UAE: Availability, Quality & Price Considerations

Ashwagandha is widely available in the UAE through:

  • Pharmacies

  • Online wellness retailers

  • Sports nutrition stores

When evaluating ashwagandha price in UAE or choosing the best ashwagandha brand, consider:

  • Standardized extract with stated withanolide percentage

  • Third-party testing

  • Clear labeling of dosage per capsule

Cheaper products often use low-potency powders without standardization, which can reduce effectiveness.

Common Myths and Misuse

Myth

Reality

“More is better”

Higher doses increase side effects, not benefits

“It works immediately”

Effects build over 2–6 weeks

“It boosts hormones for everyone”

Benefits depend on baseline status

 

References

  1. Chandrasekhar, K., Kapoor, J., & Anishetty, S. (2012). A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of Ashwagandha root in reducing stress and anxiety in adults. Indian Journal of Psychological Medicine, 34(3), 255–262. https://doi.org/10.4103/0253-7176.106022

  2. Lopresti, A. L., Smith, S. J., Malvi, H., & Kodgule, R. (2019). An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study. Medicine, 98(37), e17186. https://doi.org/10.1097/MD.0000000000017186

  3. Wankhede, S., Langade, D., Joshi, K., Sinha, S. R., & Bhattacharyya, S. (2015). Examining the effect of Withania somnifera supplementation on muscle strength and recovery: A randomized controlled trial. Journal of the International Society of Sports Nutrition, 12, 43. https://doi.org/10.1186/s12970-015-0104-9

  4. Ambiye, V. R., Langade, D., Dongre, S., Aptikar, P., Kulkarni, M., & Dongre, A. (2013). Clinical evaluation of the spermatogenic activity of the root extract of Ashwagandha (Withania somnifera) in oligospermic males. Evidence-Based Complementary and Alternative Medicine, 2013, 571420. https://doi.org/10.1155/2013/571420

  5. Salve, J., Pate, S., Debnath, K., & Langade, D. (2019). Adaptogenic and anxiolytic effects of ashwagandha root extract in healthy adults: A double-blind, randomized, placebo-controlled clinical study. Cureus, 11(12), e6466. https://doi.org/10.7759/cureus.6466

  6. Tandon, N., Yadav, S. S., & Sharma, S. (2020). Safety profile of Withania somnifera (Ashwagandha): A systematic review. Journal of Ayurveda and Integrative Medicine, 11(3), 1–9. https://doi.org/10.1016/j.jaim.2018.12.001

  7. NIH National Center for Complementary and Integrative Health (NCCIH). (2023). Ashwagandha: What you need to know. https://www.nccih.nih.gov/health/ashwagandha

  8. European Medicines Agency (EMA). (2022). Assessment report on Withania somnifera (L.) Dunal, radix. Herbal Medicinal Products Committee.

  9. Verma, N., & Gupta, S. K. (2011). Effect of Withania somnifera on cognitive dysfunction in mice. Journal of Ethnopharmacology, 135(2), 417–423. https://doi.org/10.1016/j.jep.2011.03.024

  10. Björnsson, E. S., et al. (2020). Ashwagandha-induced liver injury: A case series from Iceland and the US Drug-Induced Liver Injury Network. Liver International, 40(4), 825–829. https://doi.org/10.1111/liv.14393

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